| Cursor Keys | Movement | |
| Num Pad | Movement | |
| CTRL | Fire Laser | |
| SHIFT | Throw Grenade | |
| SPACE | Activate Shield | |
| S | Save game | |
| Q | Quit current game and return to main menu | |
| F1 | Full Screen | |
| F2 | Windowed | |
| ESC | Pause/Resume Game | |
When you start rE/Gen, it will begin in fullscreen mode. Use the menu or the function keys to switch between fullscreen and windowed mode. You can skip the intro by holding down the spacebar.
It may take some time to get used to the control scheme, but once you do it will seem natural. Experiment with the controls on the first game screen to get a feel for them.

The laser pistol is a critical item that you will need to find as soon as possible. Not only will it allow you to defend yourself, but the reflective laser shots it fires can be useful for hitting switches from a distance.
Once you find the laser, fire it with the CTRL key. You can fire multiple shots, and shots will ricochet off of walls and some objects. Normal door switches can be activated with laser shots.
Be warned, while your shots won't hurt yourself (thanks to the combat defense jumpsuit you wear), it will harm other people. So watch your shots!
Some objects and enemies cannot be harmed by the laser. You will need to find plasma grenades or other means of dealing with them.
The laser has unlimited shots, thanks to a small nuclear power source.
Caution: Extended use may cause sterility.

Plasma grenades are small magnetic bottles containing plasma energy. They do much more damage than the laser, but are single-use items.
You throw a plasma grenade by tapping the SHIFT key. Your current stock of grenades is shown at the bottom of the status area beside the grenade icon.
Warning: Not to be left within reach of children or junior technical staff.

The latest spin-off technology from one of Genoq's "dark matter" patents, this advanced personal force field renders the wearer immune to all harm for a brief period. It's safe for human contact, but any Neogen touching an active negation shield will be nullified. As an extra bonus, it makes you look like a photo negative when in effect.
You activate a negation shield by tapping the SPACE bar. Your current stock of shields is shown at the bottom of the status area beside the shield icon.

You will find keycards at various points during your exploration. Make sure you collect these, as certain doors will not open without the proper authorization level.
Your current authorization level is shown at the bottom of the status area beside the keycard icon.
If any door tries to close while someone (or something) is resting on it, it will wait until clear before shutting.

Electrified grids in the floor. Some will cycle on and off at different rates, others will stay on until shut down by other means. Most will simply have to be avoided.

Bouncing walls of energy. Fencers bounce in a predictable way off of walls. They destroy any person or Neogen they come in contact with.
Autonomous defense turrets. These green cyclopsian machines target any humanoid moving through a room. They fire on anyone entering their range of vision, launching plasma grenades at them. Trackers stop laser bolts without harm, but can be taken out with a grenade. (Even one fired from another Tracker.) Some sweep the room at various rates of rotation, others stand sentinel guarding a single approach.

Vents are not technically defenses, but rather part of the facilities air circulation system. However, due to the current crisis, all vents have been opened for emergency purging. Unfortunately, some of the Neogens have figured out how to move about using the vents. Clear a vent area of Neogens and then walk over the vent to close it.
After a conversation is over, guide the person to the room's exit (marked with a pink arrow). Once they are close enough to see the exit clearly, they will leave on their own. Make sure you stay in the room until they have completely exited. Once they exit the room safely, they will head back to the hydrofoil and you'll earn an extra life!
You can always end the conversation by saying "Let's go", at which point they'll want you to escort them safely to the exit.
Navigate the conversation menu by using the up/down cursor keys to select a reply, and press ENTER to speak the selected reply.
This game is freeware but not public domain. It may not be redistributed in any form without the author's consent, nor sold, nor placed into compilations without prior approval.
Thanks for playing!